Researchers have synthesized antibiotic-coated nanofibrous mats that can be used as material to dress and heal wounds caused by disease-related foot ulcers and various infections1.
Chronic wounds like diabetic foot ulcers, venous ulcers and pressure sores affect millions globally. Such wounds are difficult to heal and sometimes necessitate amputations.
To find an alternative dressing material for faster healing, scientists from the Indian Institute of Technology (IIT), Guwahati and West Bengal University of Animal and Fishery Sciences, Kolkata prepared the nanofibrous mats by blending silk protein fibroin with a polymer. The mats were then loaded with epidermal growth factor and coated with antibiotic ciprofloxacin.
Besides having capacity to contain swelling, the mats efficiently released the antibiotic which inhibited the growth of infectious bacteria.read more